منابع مشابه
Npgrj_NN_1927 923..929
In mammals, identifying the contribution of specific neurons or networks to behavior is a key challenge. Here we describe an approach that facilitates this process by enabling the rapid modulation of synaptic inhibition in defined cell populations. Binding of zolpidem, a systemically active allosteric modulator that enhances the function of the GABAA receptor, requires a phenylalanine residue (...
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The subarachnoid space, where cerebrospinal fluid (CSF) flows over the brain and spinal cord, is lined on one side by arachnoid barrier (AB) cells that form part of the blood-CSF barrier. However, despite the fact that drugs are administered into the CSF and CSF drug concentrations are used as a surrogate for brain drug concentration following systemic drug administration, the tightjunctioned A...
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We describe the creation of monodisperse microbeads of polydimethylsiloxane (PDMS) via a microfluidic approach. Using a flow-focusing configuration, a PDMS precursor solution is dispersed into microdroplets within an aqueous continuous phase. These droplets are collected and thermally cured off-chip into solid microbeads. Our microfluidic technique allows for direct integration of payloads into...
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Background: Fat and protein sources may influence whether lowcarbohydrate diets are associated with type 2 diabetes (T2D). Objective: The objective was to compare the associations of 3 lowcarbohydrate diet scores with incident T2D. Design: A prospective cohort study was conducted in participants from the Health Professionals Follow-Up Study who were free of T2D, cardiovascular disease, or cance...
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A combination of the unique hosting properties of cyclodextrins (CDs) and the peculiar UV-responsive trans–cis isomerization of the guest molecule azobenzene has endowed light-responsibility of the inclusion complex (IC). The IC of 4-aminoazobenzene (AAB) and hydroxypropyl-b-cyclodextrin (HPbCD), with its inherent viscosity from hydrogen bondings between CDs and p–p stacking between AABs, was e...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1991
ISSN: 0022-3050
DOI: 10.1136/jnnp.54.6.483